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Clinical and radiological correlations in patients with gestational trophoblastic disease
Gestational trophoblastic disease is an abnormality of pregnancy that encompasses a group of diseases that differ from each other in their propensity for regression, invasion, metastasis, and recurrence. In the past, it was common for patients with molar pregnancy to present with marked symptoms: co...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Colégio Brasileiro de Radiologia e Diagnóstico por
Imagem
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073391/ https://www.ncbi.nlm.nih.gov/pubmed/27777478 http://dx.doi.org/10.1590/0100-3984.2015.0073 |
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author | Lima, Lana de Lourdes Aguiar Parente, Raphael Câmara Medeiros Maestá, Izildinha Amim Junior, Joffre de Rezende Filho, Jorge Fonte Montenegro, Carlos Antonio Barbosa Braga, Antônio |
author_facet | Lima, Lana de Lourdes Aguiar Parente, Raphael Câmara Medeiros Maestá, Izildinha Amim Junior, Joffre de Rezende Filho, Jorge Fonte Montenegro, Carlos Antonio Barbosa Braga, Antônio |
author_sort | Lima, Lana de Lourdes Aguiar |
collection | PubMed |
description | Gestational trophoblastic disease is an abnormality of pregnancy that encompasses a group of diseases that differ from each other in their propensity for regression, invasion, metastasis, and recurrence. In the past, it was common for patients with molar pregnancy to present with marked symptoms: copious bleeding; theca lutein cysts; uterus larger than appropriate for gestational age; early preeclampsia; hyperemesis gravidarum; and hyperthyroidism. Currently, with early diagnosis made by ultrasound, most patients are diagnosed while the disease is still in the asymptomatic phase. In cases of progression to trophoblastic neoplasia, staging-typically with Doppler flow studies of the pelvis and chest X-ray, although occasionally with computed tomography or magnetic resonance imaging-is critical to the choice of an appropriate antineoplastic therapy regimen. Because it is an unusual and serious disease that affects women of reproductive age, as well as because its appropriate treatment results in high cure rates, it is crucial that radiologists be familiar with gestational trophoblastic disease, in order to facilitate its early diagnosis and to ensure appropriate follow-up imaging. |
format | Online Article Text |
id | pubmed-5073391 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Colégio Brasileiro de Radiologia e Diagnóstico por
Imagem |
record_format | MEDLINE/PubMed |
spelling | pubmed-50733912016-10-24 Clinical and radiological correlations in patients with gestational trophoblastic disease Lima, Lana de Lourdes Aguiar Parente, Raphael Câmara Medeiros Maestá, Izildinha Amim Junior, Joffre de Rezende Filho, Jorge Fonte Montenegro, Carlos Antonio Barbosa Braga, Antônio Radiol Bras Review Article Gestational trophoblastic disease is an abnormality of pregnancy that encompasses a group of diseases that differ from each other in their propensity for regression, invasion, metastasis, and recurrence. In the past, it was common for patients with molar pregnancy to present with marked symptoms: copious bleeding; theca lutein cysts; uterus larger than appropriate for gestational age; early preeclampsia; hyperemesis gravidarum; and hyperthyroidism. Currently, with early diagnosis made by ultrasound, most patients are diagnosed while the disease is still in the asymptomatic phase. In cases of progression to trophoblastic neoplasia, staging-typically with Doppler flow studies of the pelvis and chest X-ray, although occasionally with computed tomography or magnetic resonance imaging-is critical to the choice of an appropriate antineoplastic therapy regimen. Because it is an unusual and serious disease that affects women of reproductive age, as well as because its appropriate treatment results in high cure rates, it is crucial that radiologists be familiar with gestational trophoblastic disease, in order to facilitate its early diagnosis and to ensure appropriate follow-up imaging. Colégio Brasileiro de Radiologia e Diagnóstico por Imagem 2016 /pmc/articles/PMC5073391/ /pubmed/27777478 http://dx.doi.org/10.1590/0100-3984.2015.0073 Text en © Colégio Brasileiro de Radiologia e Diagnóstico por Imagem http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Lima, Lana de Lourdes Aguiar Parente, Raphael Câmara Medeiros Maestá, Izildinha Amim Junior, Joffre de Rezende Filho, Jorge Fonte Montenegro, Carlos Antonio Barbosa Braga, Antônio Clinical and radiological correlations in patients with gestational trophoblastic disease |
title | Clinical and radiological correlations in patients with gestational
trophoblastic disease |
title_full | Clinical and radiological correlations in patients with gestational
trophoblastic disease |
title_fullStr | Clinical and radiological correlations in patients with gestational
trophoblastic disease |
title_full_unstemmed | Clinical and radiological correlations in patients with gestational
trophoblastic disease |
title_short | Clinical and radiological correlations in patients with gestational
trophoblastic disease |
title_sort | clinical and radiological correlations in patients with gestational
trophoblastic disease |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073391/ https://www.ncbi.nlm.nih.gov/pubmed/27777478 http://dx.doi.org/10.1590/0100-3984.2015.0073 |
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