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dupRadar: a Bioconductor package for the assessment of PCR artifacts in RNA-Seq data
BACKGROUND: PCR clonal artefacts originating from NGS library preparation can affect both genomic as well as RNA-Seq applications when protocols are pushed to their limits. In RNA-Seq however the artifactual reads are not easy to tell apart from normal read duplication due to natural over-sequencing...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073875/ https://www.ncbi.nlm.nih.gov/pubmed/27769170 http://dx.doi.org/10.1186/s12859-016-1276-2 |