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Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression

We introduce the Microenvironment Cell Populations-counter (MCP-counter) method, which allows the robust quantification of the absolute abundance of eight immune and two stromal cell populations in heterogeneous tissues from transcriptomic data. We present in vitro mRNA mixture and ex vivo immunohis...

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Detalles Bibliográficos
Autores principales:	Becht, Etienne, Giraldo, Nicolas A., Lacroix, Laetitia, Buttard, Bénédicte, Elarouci, Nabila, Petitprez, Florent, Selves, Janick, Laurent-Puig, Pierre, Sautès-Fridman, Catherine, Fridman, Wolf H., de Reyniès, Aurélien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073889/ https://www.ncbi.nlm.nih.gov/pubmed/27765066 http://dx.doi.org/10.1186/s13059-016-1070-5

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