Aortic valve replacement for Libman-Sacks endocarditis

A 24-year-old man with systemic lupus erythematosus and antiphospholipid syndrome complicated by lupus nephritis presented with acute limb ischaemia secondary to an embolus. Following embolectomy, the patient underwent a transthoracic echocardiogram which revealed a large vegetation on all three cus...

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Autores principales: Keenan, Jack B, Janardhanan, Rajesh, Larsen, Brandon T, Khalpey, Zain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073913/
https://www.ncbi.nlm.nih.gov/pubmed/27702929
http://dx.doi.org/10.1136/bcr-2016-215914
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author Keenan, Jack B
Janardhanan, Rajesh
Larsen, Brandon T
Khalpey, Zain
author_facet Keenan, Jack B
Janardhanan, Rajesh
Larsen, Brandon T
Khalpey, Zain
author_sort Keenan, Jack B
collection PubMed
description A 24-year-old man with systemic lupus erythematosus and antiphospholipid syndrome complicated by lupus nephritis presented with acute limb ischaemia secondary to an embolus. Following embolectomy, the patient underwent a transthoracic echocardiogram which revealed a large vegetation on all three cusps of the aortic valve. The patient was taken for an urgent aortic valve replacement with a mechanical valve. Cultures of one cusp remained sterile. Histopathological examination of the remaining two cusps revealed sterile fibrin-rich thrombotic vegetations characteristic of non-bacterial thrombotic endocarditis.
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spelling pubmed-50739132016-11-14 Aortic valve replacement for Libman-Sacks endocarditis Keenan, Jack B Janardhanan, Rajesh Larsen, Brandon T Khalpey, Zain BMJ Case Rep Article A 24-year-old man with systemic lupus erythematosus and antiphospholipid syndrome complicated by lupus nephritis presented with acute limb ischaemia secondary to an embolus. Following embolectomy, the patient underwent a transthoracic echocardiogram which revealed a large vegetation on all three cusps of the aortic valve. The patient was taken for an urgent aortic valve replacement with a mechanical valve. Cultures of one cusp remained sterile. Histopathological examination of the remaining two cusps revealed sterile fibrin-rich thrombotic vegetations characteristic of non-bacterial thrombotic endocarditis. BMJ Publishing Group 2016-10-04 /pmc/articles/PMC5073913/ /pubmed/27702929 http://dx.doi.org/10.1136/bcr-2016-215914 Text en 2016 BMJ Publishing Group Ltd This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Article
Keenan, Jack B
Janardhanan, Rajesh
Larsen, Brandon T
Khalpey, Zain
Aortic valve replacement for Libman-Sacks endocarditis
title Aortic valve replacement for Libman-Sacks endocarditis
title_full Aortic valve replacement for Libman-Sacks endocarditis
title_fullStr Aortic valve replacement for Libman-Sacks endocarditis
title_full_unstemmed Aortic valve replacement for Libman-Sacks endocarditis
title_short Aortic valve replacement for Libman-Sacks endocarditis
title_sort aortic valve replacement for libman-sacks endocarditis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073913/
https://www.ncbi.nlm.nih.gov/pubmed/27702929
http://dx.doi.org/10.1136/bcr-2016-215914
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AT khalpeyzain aorticvalvereplacementforlibmansacksendocarditis

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