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Accurate and Rigorous Prediction of the Changes in Protein Free Energies in a Large‐Scale Mutation Scan
The prediction of mutation‐induced free‐energy changes in protein thermostability or protein–protein binding is of particular interest in the fields of protein design, biotechnology, and bioengineering. Herein, we achieve remarkable accuracy in a scan of 762 mutations estimating changes in protein t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074281/ https://www.ncbi.nlm.nih.gov/pubmed/27122231 http://dx.doi.org/10.1002/anie.201510054 |