TIM-3 is not essential for development of airway inflammation induced by house dust mite antigens

BACKGROUND: T cell immunoglobulin domain and mucin domain-containing molecule 3 (TIM-3), which is preferentially expressed on Th1 cells rather than Th2 cells, is considered to be a negative regulator of Th1 cell function. This suggests that TIM-3 indirectly enhances Th2-type immune responses by supp...

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Detalles Bibliográficos
Autores principales: Hiraishi, Yoshihisa, Nambu, Aya, Shibui, Akiko, Nakanishi, Wakako, Yamaguchi, Sachiko, Morita, Hideaki, Iikura, Motoyasu, McKenzie, Andrew N.J., Matsumoto, Kenji, Sudo, Katsuko, Yamasoba, Tatsuya, Nagase, Takahide, Nakae, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074363/
https://www.ncbi.nlm.nih.gov/pubmed/27209052
http://dx.doi.org/10.1016/j.alit.2016.04.008

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