Cargando…
Cooperative Stimulation of Megakaryocytic Differentiation by Gfi1b Gene Targets Kindlin3 and Talin1
Understanding the production and differentiation of megakaryocytes from progenitors is crucial for realizing the biology and functions of these vital cells. Previous gene ablation studies demonstrated the essential role of the transcriptional repressor Gfi1b (growth factor independence 1b) in the ge...
Autores principales: | Singh, Divya, Upadhyay, Ghanshyam, Sengupta, Ananya, Biplob, Mohammed A., Chakyayil, Shaleen, George, Tiji, Saleque, Shireen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074496/ https://www.ncbi.nlm.nih.gov/pubmed/27768697 http://dx.doi.org/10.1371/journal.pone.0164506 |
Ejemplares similares
-
Differential Transcriptional Regulation of meis1 by Gfi1b and Its Co-Factors LSD1 and CoREST
por: Chowdhury, Asif H., et al.
Publicado: (2013) -
Mechanism of integrin activation by talin and its cooperation with kindlin
por: Lu, Fan, et al.
Publicado: (2022) -
Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin
por: Theodosiou, Marina, et al.
Publicado: (2016) -
Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes
por: Beauchemin, Hugues, et al.
Publicado: (2017) -
Kindlins, Integrin Activation and the Regulation of Talin Recruitment to αIIbβ3
por: Kahner, Bryan N., et al.
Publicado: (2012)