rLj-RGD3, a Novel Recombinant Toxin Protein from Lampetra japonica, Protects against Cerebral Reperfusion Injury Following Middle Cerebral Artery Occlusion Involving the Integrin-PI3K/Akt Pathway in Rats

BACKGROUND: The RGD-toxin protein Lj-RGD3 is a naturally occurring 118 amino acid peptide that can be obtained from the salivary gland of the Lampetra japonica fish. This unique peptide contains 3 RGD (Arg-Gly-Asp) motifs in its primary structure. Lj-RGD3 is available in recombinant form (rLj-RGD3)...

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Detalles Bibliográficos
Autores principales: Lu, Qian, Wang, Jihong, Jiang, Junshu, Wang, Shengnan, Jia, Qilan, Wang, Yue, Li, Weiping, Zhou, Qin, Lv, Li, Li, Qingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074578/
https://www.ncbi.nlm.nih.gov/pubmed/27768719
http://dx.doi.org/10.1371/journal.pone.0165093

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