Effects of Neurotrophic Support and Amyloid-Targeted Combined Therapy on Adult Hippocampal Neurogenesis in a Transgenic Model of Alzheimer's Disease

Although it is recognized that multi-drug therapies may be necessary to combat AD, there is a paucity of preclinical proof of concept studies. We present a combination treatment paradigm, which temporally affects different aspects of Alzheimer’s disease (AD)-like pathology, specifically Aβ-toxicity...

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Detalles Bibliográficos
Autores principales: Morrone, Christopher D., Thomason, Lynsie A. M., Brown, Mary E., Aubert, Isabelle, McLaurin, JoAnne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074589/
https://www.ncbi.nlm.nih.gov/pubmed/27768761
http://dx.doi.org/10.1371/journal.pone.0165393

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