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Long-Range Signaling in MutS and MSH Homologs via Switching of Dynamic Communication Pathways
Allostery is conformation regulation by propagating a signal from one site to another distal site. This study focuses on the long-range communication in DNA mismatch repair proteins MutS and its homologs where intramolecular signaling has to travel over 70 Å to couple lesion detection to ATPase acti...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074593/ https://www.ncbi.nlm.nih.gov/pubmed/27768684 http://dx.doi.org/10.1371/journal.pcbi.1005159 |