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Local analgesic effect of tramadol is mediated by opioid receptors in late postoperative pain after plantar incision in rats
Tramadol is a drug used to treat moderate to severe pain. It is known to present a peripheral effect, but the local mechanisms underlying its actions remain unclear. The role of peripheral opioid receptors in postoperative pain is not well understood. In the present study, we examined the peripheral...
Autores principales: | de Oliveira Junior, José Oswaldo, de Freitas, Milena Fernandes, Bullara de Andrade, Carolina, Chacur, Marucia, Ashmawi, Hazem Adel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074711/ https://www.ncbi.nlm.nih.gov/pubmed/27799813 http://dx.doi.org/10.2147/JPR.S117674 |
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