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Optimizing superparamagnetic iron oxide nanoparticles as drug carriers using an in vitro blood–brain barrier model
In the current study, an optimized in vitro blood–brain barrier (BBB) model was established using mouse brain endothelial cells (b.End3) and astrocytes (C8-D1A). Before measuring the permeability of superparamagnetic iron oxide nanoparticle (SPION) samples, the BBB was first examined and confirmed b...
Autores principales: | Shi, Di, Mi, Gujie, Bhattacharya, Soumya, Nayar, Suprabha, Webster, Thomas J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074712/ https://www.ncbi.nlm.nih.gov/pubmed/27799764 http://dx.doi.org/10.2147/IJN.S108333 |
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