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A suppressive effect of prostaglandin E(2) on the expression of SERPINE1/plasminogen activator inhibitor-1 in human articular chondrocytes: An in vitro pilot study

Prostaglandin E(2) (PGE(2)) is expressed in articular joints with inflammatory arthropathy and may exert catabolic effects leading to cartilage degradation. As we observed in a preliminary experiment that PGE(2) suppressed the expression of SERPINE1/plasminogen activator inhibitor (PAI)-1 mRNA in ch...

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Detalles Bibliográficos
Autores principales:	Masuko, Kayo, Murata, Minako, Suematsu, Naoya, Okamoto, Kazuki, Yudoh, Kazuo, Shimizu, Hiroyuki, Beppu, Moroe, Nakamura, Hiroshi, Kato, Tomohiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2009
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074716/ https://www.ncbi.nlm.nih.gov/pubmed/27789978

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