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Recent advances in neutralizing the IL-6 pathway in arthritis

Recent advances in understanding the mechanism(s) of how IL-6 trans-signaling regulates immune cell function and promotes inflammation in autoimmune arthritis are critically reviewed. Serum and/or synovial fluid (SF) IL-6 is markedly elevated in adult and juvenile rheumatoid arthritis (RA), psoriati...

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Detalles Bibliográficos
Autor principal: Malemud, Charles J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074717/
https://www.ncbi.nlm.nih.gov/pubmed/27789987