Cargando…

Biomarkers in critical illness: have we made progress?

Biomarkers have emerged as exemplary key players in translational medicine. Many have been assessed for timely recognition, early treatment, and adequate follow-up for a variety of pathologies. Biomarker sensitivity has improved considerably over the last years but specificity remains poor, in parti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Honore, Patrick M, Jacobs, Rita, Hendrickx, Inne, De Waele, Elisabeth, Van Gorp, Viola, Joannes-Boyau, Olivier, De Regt, Jouke, Boer, Willem, Spapen, Herbert D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074734/ https://www.ncbi.nlm.nih.gov/pubmed/27799811 http://dx.doi.org/10.2147/IJNRD.S113219

Ejemplares similares

A fresh look into the pathophysiology of ischemia-induced complications in patients with chronic kidney disease undergoing hemodialysis
por: Honore, Patrick M, et al.
Publicado: (2015)

Critical care nephrology: could it be a model of multidisciplinarity in ICU nowadays for other sub-specialities – the jury is out
por: Honoré, Patrick M, et al.
Publicado: (2014)

Nebulized colistin for treatment of ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: we still need to straighten out the dose!
por: Honore, Patrick M., et al.
Publicado: (2015)

Acute respiratory muscle weakness and apnea in a critically ill patient induced by colistin neurotoxicity: key potential role of hemoadsorption elimination during continuous venovenous hemofiltration
por: Honore, Patrick M, et al.
Publicado: (2013)

Biomarkers for early diagnosis of AKI in the ICU: ready for prime time use at the bedside?
por: Honore, Patrick M, et al.
Publicado: (2012)

Prevention and treatment of sepsis-induced acute kidney injury: an update
por: Honore, Patrick M., et al.
Publicado: (2015)

Septic AKI in ICU patients. diagnosis, pathophysiology, and treatment type, dosing, and timing: a comprehensive review of recent and future developments
por: Honore, Patrick M, et al.
Publicado: (2011)

Colistin dosing for treatment of multidrug-resistant Pseudomonas in critically ill patients - please, be adequate!
por: Honoré, Patrick M, et al.
Publicado: (2014)

Biomarker validity in the critically ill: all must face the (continuous) renal replacement challenge!
por: Honore, Patrick M., et al.
Publicado: (2015)

Continuous renal replacement therapy for safe and adequate voriconazole intravenous treatment: enough reason to be confident?
por: Honore, Patrick M, et al.
Publicado: (2015)

‘Biomarking’ infection during continuous renal replacement therapy: still relevant?
por: Honore, Patrick M, et al.
Publicado: (2015)

Renal tubular acidosis with hyperchloremic acidosis: harmless with a sting?
por: Honore, Patrick M., et al.
Publicado: (2015)

Fondaparinux: another potential treatment for heparin-induced thrombocytopenia type II?
por: Honore, Patrick M., et al.
Publicado: (2016)

Optimizing citrate dose for regional anticoagulation in continuous renal replacement therapy: measuring citrate concentrations instead of ionized calcium?
por: Honore, Patrick M., et al.
Publicado: (2015)

To counteract or to clear high-mobility group box-1 protein in influenza A (H1N1) infection? That may become the question
por: Honore, Patrick M., et al.
Publicado: (2015)

Higher colistin dose during continuous renal replacement therapy: look before leaping!
por: Honore, Patrick M., et al.
Publicado: (2015)

Peri-operative fluid strategy and post-operative acute kidney injury in cardiac surgery patients: any role for pre-operative statin therapy?
por: Honore, Patrick M., et al.
Publicado: (2015)

Meropenem therapy in extracorporeal membrane oxygenation patients: an ongoing pharmacokinetic challenge
por: Honore, Patrick M., et al.
Publicado: (2015)

Presepsin and sepsis-induced acute kidney injury treated with continuous renal replacement therapy: will another promising biomarker bite the dust?
por: Honore, Patrick M., et al.
Publicado: (2015)

Predicting acute kidney injury in severe trauma. A biomarker breakthrough?
por: Honore, Patrick M., et al.
Publicado: (2015)

Metabolic and coagulation effects of citrate: down to the last detail!
por: Honore, Patrick M., et al.
Publicado: (2015)

Is neutrophil gelatinase-associated lipocalin unaffected by convective continuous renal replacement therapy? Definitely … maybe
por: Honore, Patrick M., et al.
Publicado: (2015)

Phosphate induced crystal acute kidney injury – an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature
por: Lochy, S, et al.
Publicado: (2013)

Facing acid–base disorders in the third millennium – the Stewart approach revisited
por: Kishen, R, et al.
Publicado: (2014)

High-frequency percussive ventilation in acute respiratory distress syndrome: knocking at the door but can it be let in?
por: Spapen, Herbert, et al.
Publicado: (2018)

The blind spot in high-dose tigecycline pharmacokinetics in critically ill patients: membrane adsorption during continuous extracorporeal treatment
por: Honore, Patrick M, et al.
Publicado: (2015)

What's new in emergencies, trauma, and shock: Intentional or accidental hypothermia in Intensive Care Unit patients: Time to strike the colors?
por: Honore, Patrick M., et al.
Publicado: (2016)

Alleviating central venous oxygen saturation (S(cv)O(2)): a new approach of kidney protection after cardiac surgery?
por: Honore, Patrick M., et al.
Publicado: (2015)

Colistin pharmacokinetics/pharmacodynamics and acute kidney injury: A difficult but reasonable marriage
por: Honore, Patrick M., et al.
Publicado: (2014)

An endotracheal tube providing “pressurized sealing” prevents fluid leakage in mechanically ventilated critically ill patients: a pilot study
por: Spapen, Herbert, et al.
Publicado: (2019)

Renal and neurological side effects of colistin in critically ill patients
por: Spapen, Herbert, et al.
Publicado: (2011)

Anidulafungin dosing during CRRT: do not underestimate adsorption!
por: Honore, Patrick M, et al.
Publicado: (2014)

New generation indirect calorimeters for measuring energy expenditure in the critically ill: a rampant or reticent revolution?
por: De Waele, Elisabeth, et al.
Publicado: (2016)

VCO(2) calorimetry: stop tossing stones, it’s time for building!
por: De Waele, Elisabeth, et al.
Publicado: (2016)

Cytokine removal in human septic shock: Where are we and where are we going?
por: Honore, Patrick M., et al.
Publicado: (2019)

Bedside Calculation of Energy Expenditure Does Not Guarantee Adequate Caloric Prescription in Long-Term Mechanically Ventilated Critically Ill Patients: A Quality Control Study
por: De Waele, Elisabeth, et al.
Publicado: (2012)

Normal saline as resuscitation fluid in critically ill patients: not dead yet!
por: Honore, Patrick M., et al.
Publicado: (2016)

Boerhaave's Syndrome: Still a Diagnostic and Therapeutic Challenge in the 21st Century
por: Spapen, J., et al.
Publicado: (2013)

Does discontinuation of the use of hydroxyethyl starches in the critically ill cardiac surgery patient have an impact on caloric intake?
por: Waele, E De, et al.
Publicado: (2015)

High-frequency percussive ventilation in severe acute respiratory distress syndrome: A single center experience
por: Spapen, Herbert, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_li63jbl9vf5abak824ifatqtqr