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Simultaneous Esophageal and Gastric Ulceration Due to Doxycycline Ingestion: Case Report and Review of the Literature

Doxycycline induced mucosal injury to the esophagus and, rarely, stomach is an under appreciated cause of odonyphagia and chest pain. The diagnosis is dependent on a comprehensive exposure history and endoscopic evaluation. Once recognized, doxycycline induced ulceration is easily treated with cessa...

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Detalles Bibliográficos
Autores principales: Leber, Aviva, Stal, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074820/
https://www.ncbi.nlm.nih.gov/pubmed/27785214
http://dx.doi.org/10.4021/gr498w
Descripción
Sumario:Doxycycline induced mucosal injury to the esophagus and, rarely, stomach is an under appreciated cause of odonyphagia and chest pain. The diagnosis is dependent on a comprehensive exposure history and endoscopic evaluation. Once recognized, doxycycline induced ulceration is easily treated with cessation of the medication and gastric acid suppression. Our case report describes a classic description of doxycyline induced esophageal ulceration with the unusual endoscopic finding of a simultaneous antral ulcer.