Radiation dosimetry of the α(4)β(2) nicotinic receptor ligand (+)-[(18)F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results

BACKGROUND: Both enantiomers of [(18)F]flubatine are new radioligands for neuroimaging of α(4)β(2) nicotinic acetylcholine receptors with positron emission tomography (PET) exhibiting promising pharmacokinetics which makes them attractive for different clinical questions. In a previous preclinical s...

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Detalles Bibliográficos
Autores principales: Kranz, Mathias, Sattler, Bernhard, Tiepolt, Solveig, Wilke, Stephan, Deuther-Conrad, Winnie, Donat, Cornelius K., Fischer, Steffen, Patt, Marianne, Schildan, Andreas, Patt, Jörg, Smits, René, Hoepping, Alexander, Steinbach, Jörg, Sabri, Osama, Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074934/
https://www.ncbi.nlm.nih.gov/pubmed/27770429
http://dx.doi.org/10.1186/s40658-016-0160-5

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