Cargando…

PNPLA3 as a Genetic Determinant of Risk for and Severity of Non-alcoholic Fatty Liver Disease Spectrum

Background and Aims: Patatin-like phospholipase domain protein 3 (PNPLA3) polymorphisms (rs738409 C>G) are associated with non-alcoholic fatty liver disease (NAFLD). We performed a systematic review and meta-analysis to examine the association of PNPLA3 polymorphisms with the spectrum and severit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salameh, Habeeb, Hanayneh, Muhannad Al, Masadeh, Maen, Naseemuddin, Mohammed, Matin, Tasnia, Erwin, Angelika, Singal, Ashwani K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	XIA & HE Publishing Inc. 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075002/ https://www.ncbi.nlm.nih.gov/pubmed/27777887 http://dx.doi.org/10.14218/JCTH.2016.00009

Ejemplares similares

PNPLA3 polymorphism increases risk for and severity of chronic hepatitis C liver disease
por: Salameh, Habeeb, et al.
Publicado: (2016)

Case series on multimodal endoscopic therapy for gastric antral vascular ectasia, a tertiary center experience
por: Matin, Tasnia, et al.
Publicado: (2018)

PNPLA3 GG Genotype and Carotid Atherosclerosis in Patients with Non-Alcoholic Fatty Liver Disease
por: Petta, Salvatore, et al.
Publicado: (2013)

PNPLA3-I148M: a problem of plenty in non-alcoholic fatty liver disease
por: BasuRay, Soumik
Publicado: (2019)

PNPLA3 Expression Is Related to Liver Steatosis in Morbidly Obese Women with Non-Alcoholic Fatty Liver Disease
por: Aragonès, Gemma, et al.
Publicado: (2016)

Diabetes Mellitus Predicts Occurrence of Cirrhosis and Hepatocellular Cancer in Alcoholic Liver and Non-alcoholic Fatty Liver Diseases
por: Raff, Evan J., et al.
Publicado: (2015)

Genetic Variants in PNPLA3 and Risk of Non-Alcoholic Fatty Liver Disease in a Han Chinese Population
por: Peng, Xian-E, et al.
Publicado: (2012)

SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy
por: Kim, Kwang-Youn, et al.
Publicado: (2016)

Incidence, Mortality and Predictors of Acute Kidney Injury in Patients with Cirrhosis: A Systematic Review and Meta-analysis
por: Tariq, Raseen, et al.
Publicado: (2020)

Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese
por: Kawaguchi, Takahisa, et al.
Publicado: (2012)

Corrigendum: SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy
por: Kim, Kwang-Youn, et al.
Publicado: (2016)

The role of PNPLA3 (rs738409) c>g variant on histological progression of non-alcoholic fatty liver disease
por: Idilman, Ramazan, et al.
Publicado: (2020)

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
por: Romeo, Stefano, et al.
Publicado: (2008)

Global burden of cirrhosis and liver cancer due to alcohol: the past, present, and the future
por: Xie, Chencheng, et al.
Publicado: (2023)

Covid-19 and alcohol associated liver disease
por: Deutsch-Link, Sasha, et al.
Publicado: (2022)

Influence of the PNPLA3 rs738409 Polymorphism on Non-Alcoholic Fatty Liver Disease and Renal Function among Normal Weight Subjects
por: Oniki, Kentaro, et al.
Publicado: (2015)

PNPLA3 rs738409 underlies treatment response in nonalcoholic fatty liver disease
por: Wang, Jin-Zhi, et al.
Publicado: (2018)

Endoscopic ultrasound guided liver biopsy for parenchymal liver disease
por: Shah, Aun Raza, et al.
Publicado: (2019)

A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease
por: Zain, Shamsul Mohd, et al.
Publicado: (2012)

Mitochondrial dysfunction and alcohol-associated liver disease: a novel pathway and therapeutic target
por: Abdallah, Mohamed A., et al.
Publicado: (2020)

Therapeutic targets in alcohol-associated liver disease: progress and challenges
por: Adekunle, Ayooluwatomiwa Deborah, et al.
Publicado: (2023)

Integrated Multidisciplinary Management of Alcohol-associated Liver Disease
por: Holbeck, Malia, et al.
Publicado: (2023)

Portal vein thrombosis leading to pre-sinusoidal non-cirrhotic portal hypertension resulting in decreased synthetic function of the liver
por: Kline, Kevin, et al.
Publicado: (2019)

Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease
por: Hotta, Kikuko, et al.
Publicado: (2010)

Association between the PNPLA3 I148M Polymorphism and Non-Alcoholic Fatty Liver Disease in the Uygur and Han Ethnic Groups of Northwestern China
por: Zhang, Yuexin, et al.
Publicado: (2014)

Additive Effects of the Risk Alleles of PNPLA3 and TM6SF2 on Non-alcoholic Fatty Liver Disease (NAFLD) in a Chinese Population
por: Wang, Xiaoliang, et al.
Publicado: (2016)

Expression of Concern: Influence of the PNPLA3 rs738409 Polymorphism on Non-Alcoholic Fatty Liver Disease and Renal Function among Normal Weight Subjects
Publicado: (2023)

Non-alcoholic fatty liver disease-related hepatocellular carcinoma
por: Daher, Darine, et al.
Publicado: (2023)

Transcriptional regulation of PNPLA3 and its impact on susceptibility to nonalcoholic fatty liver Disease (NAFLD) in humans
por: Liu, Wanqing, et al.
Publicado: (2016)

PNPLA3 and TM6SF2 polymorphisms in Brazilian patients with nonalcoholic fatty liver disease
por: Lisboa, Quelson Coelho, et al.
Publicado: (2020)

Editorial: Alcohol-associated liver disease—From pathogenesis to treatment
por: Kharbanda, Kusum K., et al.
Publicado: (2022)

PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress
por: Carpino, Guido, et al.
Publicado: (2017)

Hepatocellular carcinoma surveillance in patients with non-alcoholic fatty liver disease
por: Seif El Dahan, Karim, et al.
Publicado: (2023)

The i148m Pnpla3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls
por: Valenti, Luca, et al.
Publicado: (2012)

No Correlation between PNPLA3 rs738409 Genotype and Fatty Liver and Hepatic Cirrhosis in Japanese Patients with HCV
por: Nakamura, Masato, et al.
Publicado: (2013)

Genetic Polymorphisms of PNPLA3 and SAMM50 Are Associated with Nonalcoholic Fatty Liver Disease in a Korean Population
por: Chung, Goh Eun, et al.
Publicado: (2018)

PNPLA3 rs139051 is associated with phospholipid metabolite profile and hepatic inflammation in nonalcoholic fatty liver disease
por: Luo, Ji-Jun, et al.
Publicado: (2018)

Combined effects of PNPLA3, TM6SF2 and HSD17B13 variants on severity of biopsy-proven non-alcoholic fatty liver disease
por: Paternostro, Rafael, et al.
Publicado: (2021)

PNPLA3, TM6SF2, and MBOAT7 Influence on Nutraceutical Therapy Response for Non-alcoholic Fatty Liver Disease: A Randomized Controlled Trial
por: Dallio, Marcello, et al.
Publicado: (2021)

The I148M PNPLA3 variant mitigates niacin beneficial effects: How the genetic screening in non-alcoholic fatty liver disease patients gains value
por: Paolini, Erika, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ns7gsmjbuh6vggp086nrtjrq50