Supplementing Conventional Treatment with Pycnogenol® May Improve Hepatitis C Virus–Associated Type 2 Diabetes: A Mini Review

Hepatitis C virus (HCV) infection and type 2 diabetes mellitus (T2DM) present a significant health burden, with increasing complications and mortality rates worldwide. Pycnogenol® (PYC), a natural product, possesses antidiabetic and antiviral properties that may improve HCV-associated T2DM. In this...

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Autores principales: Ezzikouri, Sayeh, Jadid, Fatima Zahra, Hamdi, Salsabil, Wakrim, Lahcen, Tsukiyama-Kohara, Kyoko, Benjelloun, Soumaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075005/
https://www.ncbi.nlm.nih.gov/pubmed/27777890
http://dx.doi.org/10.14218/JCTH.2016.00021
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author Ezzikouri, Sayeh
Jadid, Fatima Zahra
Hamdi, Salsabil
Wakrim, Lahcen
Tsukiyama-Kohara, Kyoko
Benjelloun, Soumaya
author_facet Ezzikouri, Sayeh
Jadid, Fatima Zahra
Hamdi, Salsabil
Wakrim, Lahcen
Tsukiyama-Kohara, Kyoko
Benjelloun, Soumaya
author_sort Ezzikouri, Sayeh
collection PubMed
description Hepatitis C virus (HCV) infection and type 2 diabetes mellitus (T2DM) present a significant health burden, with increasing complications and mortality rates worldwide. Pycnogenol® (PYC), a natural product, possesses antidiabetic and antiviral properties that may improve HCV-associated T2DM. In this review, we present previously published data on the effectiveness of PYC against HCV replication and T2DM. We believe that supplementing conventional treatment with PYC may improve the current HCV therapy, attenuate HCV-associated T2DM, and reduce the risk of complications such as cirrhosis or hepatocellular carcinoma and cardiovascular disease.
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spelling pubmed-50750052016-10-24 Supplementing Conventional Treatment with Pycnogenol® May Improve Hepatitis C Virus–Associated Type 2 Diabetes: A Mini Review Ezzikouri, Sayeh Jadid, Fatima Zahra Hamdi, Salsabil Wakrim, Lahcen Tsukiyama-Kohara, Kyoko Benjelloun, Soumaya J Clin Transl Hepatol Review Article Hepatitis C virus (HCV) infection and type 2 diabetes mellitus (T2DM) present a significant health burden, with increasing complications and mortality rates worldwide. Pycnogenol® (PYC), a natural product, possesses antidiabetic and antiviral properties that may improve HCV-associated T2DM. In this review, we present previously published data on the effectiveness of PYC against HCV replication and T2DM. We believe that supplementing conventional treatment with PYC may improve the current HCV therapy, attenuate HCV-associated T2DM, and reduce the risk of complications such as cirrhosis or hepatocellular carcinoma and cardiovascular disease. XIA & HE Publishing Inc. 2016-07-29 2016-09-28 /pmc/articles/PMC5075005/ /pubmed/27777890 http://dx.doi.org/10.14218/JCTH.2016.00021 Text en © 2016 The Second Affiliated Hospital of Chongqing Medical University. Published by XIA & HE Publishing Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 4.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ezzikouri, Sayeh
Jadid, Fatima Zahra
Hamdi, Salsabil
Wakrim, Lahcen
Tsukiyama-Kohara, Kyoko
Benjelloun, Soumaya
Supplementing Conventional Treatment with Pycnogenol® May Improve Hepatitis C Virus–Associated Type 2 Diabetes: A Mini Review
title Supplementing Conventional Treatment with Pycnogenol® May Improve Hepatitis C Virus–Associated Type 2 Diabetes: A Mini Review
title_full Supplementing Conventional Treatment with Pycnogenol® May Improve Hepatitis C Virus–Associated Type 2 Diabetes: A Mini Review
title_fullStr Supplementing Conventional Treatment with Pycnogenol® May Improve Hepatitis C Virus–Associated Type 2 Diabetes: A Mini Review
title_full_unstemmed Supplementing Conventional Treatment with Pycnogenol® May Improve Hepatitis C Virus–Associated Type 2 Diabetes: A Mini Review
title_short Supplementing Conventional Treatment with Pycnogenol® May Improve Hepatitis C Virus–Associated Type 2 Diabetes: A Mini Review
title_sort supplementing conventional treatment with pycnogenol® may improve hepatitis c virus–associated type 2 diabetes: a mini review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075005/
https://www.ncbi.nlm.nih.gov/pubmed/27777890
http://dx.doi.org/10.14218/JCTH.2016.00021
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