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PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers

BACKGROUND: Antiarrhythmic drugs are widely used to treat patients with atrial fibrillation (AF), but the mechanisms conveying their variable effectiveness are not known. Recent data suggested that paired like homeodomain-2 transcription factor (PITX2) might play an important role in regulating gene...

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Detalles Bibliográficos
Autores principales:	Syeda, Fahima, Holmes, Andrew P., Yu, Ting Y., Tull, Samantha, Kuhlmann, Stefan Michael, Pavlovic, Davor, Betney, Daniel, Riley, Genna, Kucera, Jan P., Jousset, Florian, de Groot, Joris R., Rohr, Stephan, Brown, Nigel A., Fabritz, Larissa, Kirchhof, Paulus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Biomedical 2016
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075046/ https://www.ncbi.nlm.nih.gov/pubmed/27765191 http://dx.doi.org/10.1016/j.jacc.2016.07.766

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