Modulation of the Substitution Pattern of 5-Aryl-2-Aminoimidazoles Allows Fine-Tuning of Their Antibiofilm Activity Spectrum and Toxicity

We previously synthesized several series of compounds, based on the 5-aryl-2-aminoimidazole scaffold, that showed activity preventing the formation of Salmonella enterica serovar Typhimurium and Pseudomonas aeruginosa biofilms. Here, we further studied the activity spectrum of a number of the most a...

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Detalles Bibliográficos
Autores principales: Peeters, Elien, Hooyberghs, Geert, Robijns, Stijn, Waldrant, Kai, De Weerdt, Ami, Delattin, Nicolas, Liebens, Veerle, Kucharíková, Soňa, Tournu, Hélène, Verstraeten, Natalie, Dovgan, Barbara, Girandon, Lenart, Fröhlich, Mirjam, De Brucker, Katrijn, Van Dijck, Patrick, Michiels, Jan, Cammue, Bruno P. A., Thevissen, Karin, Vanderleyden, Jozef, Van der Eycken, Erik, Steenackers, Hans P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075052/
https://www.ncbi.nlm.nih.gov/pubmed/27550355
http://dx.doi.org/10.1128/AAC.00035-16

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