Ex vivo piperaquine resistance developed rapidly in Plasmodium falciparum isolates in northern Cambodia compared to Thailand

BACKGROUND: The recent dramatic decline in dihydroartemisinin-piperaquine (DHA-PPQ) efficacy in northwestern Cambodia has raised concerns about the rapid spread of piperaquine resistance just as DHA-PPQ is being introduced as first-line therapy in neighbouring countries. METHODS: Ex vivo parasite su...

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Detalles Bibliográficos
Autores principales: Chaorattanakawee, Suwanna, Lon, Chanthap, Jongsakul, Krisada, Gawee, Jariyanart, Sok, Somethy, Sundrakes, Siratchana, Kong, Nareth, Thamnurak, Chatchadaporn, Chann, Soklyda, Chattrakarn, Sorayut, Praditpol, Chantida, Buathong, Nillawan, Uthaimongkol, Nichapat, Smith, Philip, Sirisopana, Narongrid, Huy, Rekol, Prom, Satharath, Fukuda, Mark M., Bethell, Delia, Walsh, Douglas S., Lanteri, Charlotte, Saunders, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075182/
https://www.ncbi.nlm.nih.gov/pubmed/27769299
http://dx.doi.org/10.1186/s12936-016-1569-y

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