Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations

Humans differ in the outcome that follows exposure to life-threatening pathogens, yet the extent of population differences in immune responses and their genetic and evolutionary determinants remain undefined. Here, we characterized, using RNA sequencing, the transcriptional response of primary monoc...

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Detalles Bibliográficos
Autores principales: Quach, Hélène, Rotival, Maxime, Pothlichet, Julien, Loh, Yong-Hwee Eddie, Dannemann, Michael, Zidane, Nora, Laval, Guillaume, Patin, Etienne, Harmant, Christine, Lopez, Marie, Deschamps, Matthieu, Naffakh, Nadia, Duffy, Darragh, Coen, Anja, Leroux-Roels, Geert, Clément, Frederic, Boland, Anne, Deleuze, Jean-François, Kelso, Janet, Albert, Matthew L., Quintana-Murci, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075285/
https://www.ncbi.nlm.nih.gov/pubmed/27768888
http://dx.doi.org/10.1016/j.cell.2016.09.024

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