The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism

Apolipoprotein C-III has been referred to as an important participant in the metabolism of triglyceride-rich lipoproteins, leading to hypertriglyceridemia and thereafter cardiovascular disease. Accumulating evidence indicates that apolipoprotein C-III is a multifaceted protein which not only regulat...

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Detalles Bibliográficos
Autores principales: Luo, Mengdie, Peng, Daoquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075399/
https://www.ncbi.nlm.nih.gov/pubmed/27770802
http://dx.doi.org/10.1186/s12944-016-0352-y
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author Luo, Mengdie
Peng, Daoquan
author_facet Luo, Mengdie
Peng, Daoquan
author_sort Luo, Mengdie
collection PubMed
description Apolipoprotein C-III has been referred to as an important participant in the metabolism of triglyceride-rich lipoproteins, leading to hypertriglyceridemia and thereafter cardiovascular disease. Accumulating evidence indicates that apolipoprotein C-III is a multifaceted protein which not only regulates triglyceride metabolism, but also participates in the atherosclerotic lesion formation and several other pathological processes involved in atherosclerosis. Based on data from experiments and clinical trials, some novel therapies such as antisense technology emerge.
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spelling pubmed-50753992016-10-28 The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism Luo, Mengdie Peng, Daoquan Lipids Health Dis Review Apolipoprotein C-III has been referred to as an important participant in the metabolism of triglyceride-rich lipoproteins, leading to hypertriglyceridemia and thereafter cardiovascular disease. Accumulating evidence indicates that apolipoprotein C-III is a multifaceted protein which not only regulates triglyceride metabolism, but also participates in the atherosclerotic lesion formation and several other pathological processes involved in atherosclerosis. Based on data from experiments and clinical trials, some novel therapies such as antisense technology emerge. BioMed Central 2016-10-22 /pmc/articles/PMC5075399/ /pubmed/27770802 http://dx.doi.org/10.1186/s12944-016-0352-y Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Luo, Mengdie
Peng, Daoquan
The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism
title The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism
title_full The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism
title_fullStr The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism
title_full_unstemmed The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism
title_short The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism
title_sort emerging role of apolipoprotein c-iii: beyond effects on triglyceride metabolism
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075399/
https://www.ncbi.nlm.nih.gov/pubmed/27770802
http://dx.doi.org/10.1186/s12944-016-0352-y
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