Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling

BACKGROUND: Peripheral nerve injury is a frequent cause of lasting motor deficits and chronic pain. Although peripheral nerves are capable of regrowth they often fail to re-innervate target tissues. RESULTS: Using newly generated transgenic mice with inducible neuronal progranulin overexpression we...

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Detalles Bibliográficos
Autores principales: Altmann, Christine, Vasic, Verica, Hardt, Stefanie, Heidler, Juliana, Häussler, Annett, Wittig, Ilka, Schmidt, Mirko H. H., Tegeder, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075406/
https://www.ncbi.nlm.nih.gov/pubmed/27770818
http://dx.doi.org/10.1186/s13024-016-0132-1

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