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Combining laboratory and mathematical models to infer mechanisms underlying kinetic changes in macrophage susceptibility to an RNA virus

BACKGROUND: Macrophages are essential to innate immunity against many pathogens, but some pathogens also target macrophages as routes to infection. The Porcine Reproductive and Respiratory Syndrome virus (PRRSV) is an RNA virus that infects porcine alveolar macrophages (PAMs) causing devastating imp...

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Detalles Bibliográficos
Autores principales:	Doeschl-Wilson, Andrea, Wilson, Alison, Nielsen, Jens, Nauwynck, Hans, Archibald, Alan, Ait-Ali, Tahar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075420/ https://www.ncbi.nlm.nih.gov/pubmed/27770812 http://dx.doi.org/10.1186/s12918-016-0345-5

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