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Structure and Protein–Protein Interactions of Human UDP-Glucuronosyltransferases

Mammalian UDP-glucuronosyltransferases (UGTs) catalyze the transfer of glucuronic acid from UDP-glucuronic acid to various xenobiotics and endobiotics. Since UGTs comprise rate-limiting enzymes for metabolism of various compounds, co-administration of UGT-inhibiting drugs and genetic deficiency of U...

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Detalles Bibliográficos
Autores principales: Fujiwara, Ryoichi, Yokoi, Tsuyoshi, Nakajima, Miki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075577/
https://www.ncbi.nlm.nih.gov/pubmed/27822186
http://dx.doi.org/10.3389/fphar.2016.00388