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Hepatoid Adenocarcinoma of the Urachus

Hepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microsco...

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Detalles Bibliográficos
Autores principales: Gallego, Daniel Fernando, Muñoz, Carlos, Jimenez, Carlos Andrés, Carrascal, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075609/
https://www.ncbi.nlm.nih.gov/pubmed/27803830
http://dx.doi.org/10.1155/2016/1871807
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author Gallego, Daniel Fernando
Muñoz, Carlos
Jimenez, Carlos Andrés
Carrascal, Edwin
author_facet Gallego, Daniel Fernando
Muñoz, Carlos
Jimenez, Carlos Andrés
Carrascal, Edwin
author_sort Gallego, Daniel Fernando
collection PubMed
description Hepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microscopy the tumor resembled liver architecture, with polygonal atypical cells in nest formation and trabecular structures. Immunochemistry was positive for alfa-fetoprotein (AFP) and serum AFP was elevated. Hepatoid adenocarcinomas have been reported in multiple organs, being most commonly found in the stomach and the ovaries. Bladder compromise has been rarely described in the literature, and it has been associated with poor prognosis, low remission rates, and early metastasis.
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spelling pubmed-50756092016-11-01 Hepatoid Adenocarcinoma of the Urachus Gallego, Daniel Fernando Muñoz, Carlos Jimenez, Carlos Andrés Carrascal, Edwin Case Rep Pathol Case Report Hepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microscopy the tumor resembled liver architecture, with polygonal atypical cells in nest formation and trabecular structures. Immunochemistry was positive for alfa-fetoprotein (AFP) and serum AFP was elevated. Hepatoid adenocarcinomas have been reported in multiple organs, being most commonly found in the stomach and the ovaries. Bladder compromise has been rarely described in the literature, and it has been associated with poor prognosis, low remission rates, and early metastasis. Hindawi Publishing Corporation 2016 2016-10-10 /pmc/articles/PMC5075609/ /pubmed/27803830 http://dx.doi.org/10.1155/2016/1871807 Text en Copyright © 2016 Daniel Fernando Gallego et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gallego, Daniel Fernando
Muñoz, Carlos
Jimenez, Carlos Andrés
Carrascal, Edwin
Hepatoid Adenocarcinoma of the Urachus
title Hepatoid Adenocarcinoma of the Urachus
title_full Hepatoid Adenocarcinoma of the Urachus
title_fullStr Hepatoid Adenocarcinoma of the Urachus
title_full_unstemmed Hepatoid Adenocarcinoma of the Urachus
title_short Hepatoid Adenocarcinoma of the Urachus
title_sort hepatoid adenocarcinoma of the urachus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075609/
https://www.ncbi.nlm.nih.gov/pubmed/27803830
http://dx.doi.org/10.1155/2016/1871807
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