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ATP Induces IL-1β Secretion in Neisseria gonorrhoeae-Infected Human Macrophages by a Mechanism Not Related to the NLRP3/ASC/Caspase-1 Axis

Neisseria gonorrhoeae (Ngo) has developed multiple immune evasion mechanisms involving the innate and adaptive immune responses. Recent findings have reported that Ngo reduces the IL-1β secretion of infected human monocyte-derived macrophages (MDM). Here, we investigate the role of adenosine triphos...

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Detalles Bibliográficos
Autores principales: García, Killen, Escobar, Gisselle, Mendoza, Pablo, Beltran, Caroll, Perez, Claudio, Arancibia, Sergio, Vernal, Rolando, Rodas, Paula I., Acuña-Castillo, Claudio, Escobar, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075643/
https://www.ncbi.nlm.nih.gov/pubmed/27803513
http://dx.doi.org/10.1155/2016/1258504