Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review

INTRODUCTION: Thymic carcinoma is a rare malignancy often presenting at an advanced stage. Radiation therapy and chemotherapy are often the only treatment options available to physicians. METHODS: A 70-year-old man presented with an unresectable stage III thymic tumor and was treated with 45 Gy in 2...

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Detalles Bibliográficos
Autores principales: Dooley, Sarah A., Anderson, Carryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075761/
https://www.ncbi.nlm.nih.gov/pubmed/27822456
http://dx.doi.org/10.3389/fonc.2016.00219
Descripción
Sumario:INTRODUCTION: Thymic carcinoma is a rare malignancy often presenting at an advanced stage. Radiation therapy and chemotherapy are often the only treatment options available to physicians. METHODS: A 70-year-old man presented with an unresectable stage III thymic tumor and was treated with 45 Gy in 25 fractions followed by a boost of 21.6 Gy in 12 fractions. He was also treated with bortezomib for multiple myeloma unrelated to his primary malignancy. RESULTS: The patient made a full recovery following the radiation regimen and remained disease free 4 years after the treatment. CONCLUSION: Exclusive treatment with intensity-modulated radiation therapy provides a viable treatment option for patients presenting with advanced stage thymic carcinoma.

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