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Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review

INTRODUCTION: Thymic carcinoma is a rare malignancy often presenting at an advanced stage. Radiation therapy and chemotherapy are often the only treatment options available to physicians. METHODS: A 70-year-old man presented with an unresectable stage III thymic tumor and was treated with 45 Gy in 2...

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Autores principales: Dooley, Sarah A., Anderson, Carryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075761/
https://www.ncbi.nlm.nih.gov/pubmed/27822456
http://dx.doi.org/10.3389/fonc.2016.00219
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author Dooley, Sarah A.
Anderson, Carryn M.
author_facet Dooley, Sarah A.
Anderson, Carryn M.
author_sort Dooley, Sarah A.
collection PubMed
description INTRODUCTION: Thymic carcinoma is a rare malignancy often presenting at an advanced stage. Radiation therapy and chemotherapy are often the only treatment options available to physicians. METHODS: A 70-year-old man presented with an unresectable stage III thymic tumor and was treated with 45 Gy in 25 fractions followed by a boost of 21.6 Gy in 12 fractions. He was also treated with bortezomib for multiple myeloma unrelated to his primary malignancy. RESULTS: The patient made a full recovery following the radiation regimen and remained disease free 4 years after the treatment. CONCLUSION: Exclusive treatment with intensity-modulated radiation therapy provides a viable treatment option for patients presenting with advanced stage thymic carcinoma.
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spelling pubmed-50757612016-11-07 Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review Dooley, Sarah A. Anderson, Carryn M. Front Oncol Oncology INTRODUCTION: Thymic carcinoma is a rare malignancy often presenting at an advanced stage. Radiation therapy and chemotherapy are often the only treatment options available to physicians. METHODS: A 70-year-old man presented with an unresectable stage III thymic tumor and was treated with 45 Gy in 25 fractions followed by a boost of 21.6 Gy in 12 fractions. He was also treated with bortezomib for multiple myeloma unrelated to his primary malignancy. RESULTS: The patient made a full recovery following the radiation regimen and remained disease free 4 years after the treatment. CONCLUSION: Exclusive treatment with intensity-modulated radiation therapy provides a viable treatment option for patients presenting with advanced stage thymic carcinoma. Frontiers Media S.A. 2016-10-24 /pmc/articles/PMC5075761/ /pubmed/27822456 http://dx.doi.org/10.3389/fonc.2016.00219 Text en Copyright © 2016 Dooley and Anderson. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Dooley, Sarah A.
Anderson, Carryn M.
Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review
title Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review
title_full Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review
title_fullStr Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review
title_full_unstemmed Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review
title_short Definitive IMRT for Stage III Thymic Carcinoma: A Brief Report and Literature Review
title_sort definitive imrt for stage iii thymic carcinoma: a brief report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075761/
https://www.ncbi.nlm.nih.gov/pubmed/27822456
http://dx.doi.org/10.3389/fonc.2016.00219
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