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Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors
The stringent response is a central adaptation mechanism that allows bacteria to adjust their growth and metabolism according to environmental conditions. The functionality of the stringent response is crucial for bacterial virulence, survival during host invasion as well as antibiotic resistance an...
Autores principales: | Andresen, Liis, Varik, Vallo, Tozawa, Yuzuru, Jimmy, Steffi, Lindberg, Stina, Tenson, Tanel, Hauryliuk, Vasili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075769/ https://www.ncbi.nlm.nih.gov/pubmed/27775002 http://dx.doi.org/10.1038/srep35824 |
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