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Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition

Using matrix elasticity and cyclic stretch have been investigated for inducing mesenchymal stromal cell (MSC) differentiation towards the smooth muscle cell (SMC) lineage but not in combination. We hypothesized that combining lineage-specific stiffness with cyclic stretch would result in a significa...

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Detalles Bibliográficos
Autores principales:	Rothdiener, Miriam, Hegemann, Miriam, Uynuk-Ool, Tatiana, Walters, Brandan, Papugy, Piruntha, Nguyen, Phong, Claus, Valentin, Seeger, Tanja, Stoeckle, Ulrich, Boehme, Karen A., Aicher, Wilhelm K., Stegemann, Jan P., Hart, Melanie L., Kurz, Bodo, Klein, Gerd, Rolauffs, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075785/ https://www.ncbi.nlm.nih.gov/pubmed/27775041 http://dx.doi.org/10.1038/srep35840

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