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Fucoidan inhibits CCL22 production through NF-κB pathway in M2 macrophages: a potential therapeutic strategy for cancer

In tumor microenvironment, macrophages as a polarized M2 population promote tumor progression via releasing multiple cytokines and chemokines. A brown seaweed fucose-rich polysaccharide, fucoidan has antitumor activity and immune modulation through affecting tumor cells and lymphocytes. Here, we foc...

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Detalles Bibliográficos
Autores principales: Sun, Jia, Sun, Jintang, Song, Bingfeng, Zhang, Lin, Shao, Qianqian, Liu, Yanguo, Yuan, Daoying, Zhang, Yun, Qu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075786/
https://www.ncbi.nlm.nih.gov/pubmed/27775051
http://dx.doi.org/10.1038/srep35855