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γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis

Chronic inflammation-associated bone destruction, which is observed in rheumatoid arthritis (RA) and periodontitis, is mediated by excessive osteoclastogenesis. We showed previously that γ-glutamyltranspeptidase (GGT), an enzyme involved in glutathione metabolism, acts as an endogenous activator of...

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Detalles Bibliográficos
Autores principales:	Moriwaki, Sawako, Into, Takeshi, Suzuki, Keiko, Miyauchi, Mutsumi, Takata, Takashi, Shibayama, Keigo, Niida, Shumpei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075938/ https://www.ncbi.nlm.nih.gov/pubmed/27775020 http://dx.doi.org/10.1038/srep35930

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