Involvement of P2X7 receptor signaling on regulating the differentiation of Th17 cells and type II collagen-induced arthritis in mice

Interleukin (IL)-17 producing T helper (Th17) cells are major effector cells in the pathogenesis of rheumatoid arthritis (RA). The P2X7 receptor (P2X7R) has emerged as a potential site in the regulation of inflammation in RA but little is known of its functional role on the differentiation of Th17 c...

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Detalles Bibliográficos
Autores principales: Fan, Zhi-Dan, Zhang, Ya-Yuan, Guo, Yi-Hong, Huang, Na, Ma, Hui-Hui, Huang, Hui, Yu, Hai-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075966/
https://www.ncbi.nlm.nih.gov/pubmed/27775097
http://dx.doi.org/10.1038/srep35804

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