DNA methylation-based measures of biological age: meta-analysis predicting time to death

Estimates of biological age based on DNA methylation patterns, often referred to as “epigenetic age”, “DNAm age”, have been shown to be robust biomarkers of age in humans. We previously demonstrated that independent of chronological age, epigenetic age assessed in blood predicted all-cause mortality...

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Detalles Bibliográficos
Autores principales: Chen, Brian H., Marioni, Riccardo E., Colicino, Elena, Peters, Marjolein J., Ward-Caviness, Cavin K., Tsai, Pei-Chien, Roetker, Nicholas S., Just, Allan C., Demerath, Ellen W., Guan, Weihua, Bressler, Jan, Fornage, Myriam, Studenski, Stephanie, Vandiver, Amy R., Moore, Ann Zenobia, Tanaka, Toshiko, Kiel, Douglas P., Liang, Liming, Vokonas, Pantel, Schwartz, Joel, Lunetta, Kathryn L., Murabito, Joanne M., Bandinelli, Stefania, Hernandez, Dena G., Melzer, David, Nalls, Michael, Pilling, Luke C., Price, Timothy R., Singleton, Andrew B., Gieger, Christian, Holle, Rolf, Kretschmer, Anja, Kronenberg, Florian, Kunze, Sonja, Linseisen, Jakob, Meisinger, Christine, Rathmann, Wolfgang, Waldenberger, Melanie, Visscher, Peter M., Shah, Sonia, Wray, Naomi R., McRae, Allan F., Franco, Oscar H., Hofman, Albert, Uitterlinden, André G., Absher, Devin, Assimes, Themistocles, Levine, Morgan E., Lu, Ake T., Tsao, Philip S., Hou, Lifang, Manson, JoAnn E., Carty, Cara L., LaCroix, Andrea Z., Reiner, Alexander P., Spector, Tim D., Feinberg, Andrew P., Levy, Daniel, Baccarelli, Andrea, van Meurs, Joyce, Bell, Jordana T., Peters, Annette, Deary, Ian J., Pankow, James S., Ferrucci, Luigi, Horvath, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076441/
https://www.ncbi.nlm.nih.gov/pubmed/27690265
http://dx.doi.org/10.18632/aging.101020

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