Cargando…

PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration

Peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) is a nuclear receptor that regulates differentiation, inflammation, lipid metabolism, extracellular matrix remodeling, and angiogenesis in multiple tissues. These pathways are also central to the pathogenesis of age-related macular degeneratio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choudhary, Mayur, Ding, Jin-dong, Qi, Xiaoping, Boulton, Michael E., Yao, Pei-Li, Peters, Jeffrey M., Malek, Goldis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076447/ https://www.ncbi.nlm.nih.gov/pubmed/27622388 http://dx.doi.org/10.18632/aging.101031

Ejemplares similares

NURR1 expression regulates retinal pigment epithelial–mesenchymal transition and age-related macular degeneration phenotypes
por: Yao, Pei-Li, et al.
Publicado: (2022)

Osteopontin accumulates in basal deposits of human eyes with age-related macular degeneration and may serve as a biomarker of aging
por: Lekwuwa, Michael, et al.
Publicado: (2021)

Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention
por: Peters, Jeffrey M., et al.
Publicado: (2015)

Age-Related Macular Degeneration Revisited: From Pathology and Cellular Stress to Potential Therapies
por: Hadziahmetovic, Majda, et al.
Publicado: (2021)

The Aryl Hydrocarbon Receptor: A Mediator and Potential Therapeutic Target for Ocular and Non-Ocular Neurodegenerative Diseases
por: Choudhary, Mayur, et al.
Publicado: (2020)

A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis
por: Müller, Rolf, et al.
Publicado: (2008)

Nuclear Receptor Atlases of Choroidal Tissues Reveal Candidate Receptors Associated with Age-Related Macular Degeneration
por: Peavey, Jeremy, et al.
Publicado: (2022)

Unraveling the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) expression in colon carcinogenesis
por: Peters, Jeffrey M., et al.
Publicado: (2019)

Investigating the Role of PPARβ/δ in Retinal Vascular Remodeling Using Pparβ/δ-Deficient Mice
por: Ho, Sze Yuan, et al.
Publicado: (2020)

Skin-Targeted Inhibition of PPAR β/δ by Selective Antagonists to Treat PPAR β/δ – Mediated Psoriasis-Like Skin Disease In Vivo
por: Hack, Katrin, et al.
Publicado: (2012)

Correction: Peavey et al. Nuclear Receptor Atlases of Choroidal Tissues Reveal Candidate Receptors Associated with Age-Related Macular Degeneration. Cells 2022, 11, 2386
por: Peavey, Jeremy, et al.
Publicado: (2022)

Insights into the Role of PPARβ/δ in NAFLD
por: Chen, Jiapeng, et al.
Publicado: (2018)

PPARβ/δ: Linking Metabolism to Regeneration
por: Magadum, Ajit, et al.
Publicado: (2018)

The Role of PPARβ/δ in Melanoma Metastasis
por: Lim, Jonathan Chee Woei, et al.
Publicado: (2018)

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4
por: Khozoie, Combiz, et al.
Publicado: (2012)

PPARβ/δ and PPARγ maintain undifferentiated phenotypes of mouse adult neural precursor cells from the subventricular zone
por: Bernal, Carolina, et al.
Publicado: (2015)

A Role for PPARβ/δ in Ocular Angiogenesis
por: Bishop-Bailey, David
Publicado: (2008)

Regulation of Cell Proliferation and Differentiation by PPARβ/δ
por: Müller, Rolf, et al.
Publicado: (2008)

Time (and PPARβ/δ) heals all wounds
por: Short, Ben
Publicado: (2009)

Vascular PPARβ/δ Promotes Tumor Angiogenesis and Progression
por: Wagner, Kay-Dietrich, et al.
Publicado: (2019)

PPARβ/δ: Benefits in Coronary Artery Disease and Beyond
por: Leal, Viviane O.
Publicado: (2019)

The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance
por: Aguilar-Recarte, David, et al.
Publicado: (2021)

NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?
por: Mackenzie, Gerardo G., et al.
Publicado: (2008)

PPAR-δ in Vascular Pathophysiology
por: Wang, Nanping
Publicado: (2008)

Unraveling the Role of Peroxisome Proliferator-Activated Receptor β/Δ (PPAR β/Δ) in Angiogenesis Associated with Multiple Myeloma
por: Leone, Patrizia, et al.
Publicado: (2023)

Vaticanol C, a resveratrol tetramer, activates PPARα and PPARβ/δ in vitro and in vivo
por: Tsukamoto, Tomoko, et al.
Publicado: (2010)

PPARα and PPARβ/δ are negatively correlated with proinflammatory markers in leukocytes of an obese pediatric population
por: Vargas-Sánchez, Karina, et al.
Publicado: (2020)

PPARδ status and mismatch repair mediated neoplasia in the mouse intestine
por: Reed, Karen R, et al.
Publicado: (2006)

Integrative and systemic approaches for evaluating PPARβ/δ (PPARD) function
por: Giordano Attianese, Greta MP, et al.
Publicado: (2015)

PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders
por: Palomer, Xavier, et al.
Publicado: (2018)

PPARβ/δ-dependent MSC metabolism determines their immunoregulatory properties
por: Contreras-Lopez, R. A., et al.
Publicado: (2020)

PPAR-α Ligands as Potential Therapeutic Agents for Wet Age-Related Macular Degeneration
por: del V Cano, Marisol, et al.
Publicado: (2008)

Reverse crosstalk of TGFβ and PPARβ/δ signaling identified by transcriptional profiling
por: Stockert, Josefine, et al.
Publicado: (2011)

Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways
por: Choudhary, Mayur, et al.
Publicado: (2015)

PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
por: Glazer, Robert I., et al.
Publicado: (2008)

Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo
por: Higgins, Larry G., et al.
Publicado: (2012)

Genomewide Analyses Define Different Modes of Transcriptional Regulation by Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ)
por: Adhikary, Till, et al.
Publicado: (2011)

Emerging Role of PPAR-β/δ in Inflammatory Process Associated to Experimental Periodontitis
por: Di Paola, Rosanna, et al.
Publicado: (2011)

PPARβ/δ activation of CD300a controls intestinal immunity
por: Tanaka, Toshiya, et al.
Publicado: (2014)

Lack of PPARβ/δ-Inactivated SGK-1 Is Implicated in Liver Carcinogenesis
por: Shen, Bo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1foesp9722abknt3gm65gn7mk5