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In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state

Populations in developed nations throughout the world are rapidly aging, and the search for geroprotectors, or anti-aging interventions, has never been more important. Yet while hundreds of geroprotectors have extended lifespan in animal models, none have yet been approved for widespread use in huma...

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Detalles Bibliográficos
Autores principales: Aliper, Alexander, Belikov, Aleksey V., Garazha, Andrew, Jellen, Leslie, Artemov, Artem, Suntsova, Maria, Ivanova, Alena, Venkova, Larisa, Borisov, Nicolas, Buzdin, Anton, Mamoshina, Polina, Putin, Evgeny, Swick, Andrew G., Moskalev, Alexey, Zhavoronkov, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076455/
https://www.ncbi.nlm.nih.gov/pubmed/27677171
http://dx.doi.org/10.18632/aging.101047