Cargando…
In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state
Populations in developed nations throughout the world are rapidly aging, and the search for geroprotectors, or anti-aging interventions, has never been more important. Yet while hundreds of geroprotectors have extended lifespan in animal models, none have yet been approved for widespread use in huma...
Autores principales: | Aliper, Alexander, Belikov, Aleksey V., Garazha, Andrew, Jellen, Leslie, Artemov, Artem, Suntsova, Maria, Ivanova, Alena, Venkova, Larisa, Borisov, Nicolas, Buzdin, Anton, Mamoshina, Polina, Putin, Evgeny, Swick, Andrew G., Moskalev, Alexey, Zhavoronkov, Alex |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076455/ https://www.ncbi.nlm.nih.gov/pubmed/27677171 http://dx.doi.org/10.18632/aging.101047 |
Ejemplares similares
-
Towards natural mimetics of metformin and rapamycin
por: Aliper, Alexander, et al.
Publicado: (2017) -
Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease
por: Moskalev, Alexey, et al.
Publicado: (2015) -
Human Gut Microbiome Aging Clock Based on Taxonomic Profiling and Deep Learning
por: Galkin, Fedor, et al.
Publicado: (2020) -
Combinatorial high-throughput experimental and bioinformatic approach identifies molecular pathways linked with the sensitivity to anticancer target drugs
por: Venkova, Larisa, et al.
Publicado: (2015) -
Deep biomarkers of human aging: Application of deep neural networks to biomarker development
por: Putin, Evgeny, et al.
Publicado: (2016)