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Lateral Mobility and Nanoscale Spatial Arrangement of Chemokine-activated α4β1 Integrins on T Cells

Chemokine stimulation of integrin α4β1-dependent T lymphocyte adhesion is a key step during lymphocyte trafficking. A central question regarding α4β1 function is how its lateral mobility and organization influence its affinity and avidity following cell stimulation with chemokines and/or ligands. Us...

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Detalles Bibliográficos
Autores principales:	Sosa-Costa, Alberto, Isern de Val, Sol, Sevilla-Movilla, Silvia, Borgman, Kyra J. E., Manzo, Carlo, Teixidó, Joaquin, Garcia-Parajo, Maria F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076515/ https://www.ncbi.nlm.nih.gov/pubmed/27481944 http://dx.doi.org/10.1074/jbc.M116.733709

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