Cargando…

Bioavailability, safety, and pharmacodynamics of delayed-release dexlansoprazole administered as two 30 mg orally disintegrating tablets or one 60 mg capsule

BACKGROUND: Dual delayed-release dexlansoprazole is approved for use in adults as a 30 mg orally disintegrating tablet (ODT) or as 30 mg and 60 mg capsules. The pharmacokinetics, pharmacodynamics, and safety profile of two dexlansoprazole 30 mg ODTs were compared with one dexlansoprazole 60 mg capsu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kukulka, Michael, Nudurupati, Sai, Perez, Maria Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076775/ https://www.ncbi.nlm.nih.gov/pubmed/27803732 http://dx.doi.org/10.1177/1756283X16666800

Ejemplares similares

Pharmacokinetics and pharmacodynamics of an orally disintegrating tablet formulation of dexlansoprazole
por: Kukulka, Michael, et al.
Publicado: (2016)

Bioavailability of a dexlansoprazole delayed-release orally disintegrating tablet: effects of food and mode of administration
por: Kukulka, Michael, et al.
Publicado: (2017)

Comparator pH study to evaluate the single-dose pharmacodynamics of dual delayed-release dexlansoprazole 60 mg and delayed-release esomeprazole 40 mg
por: Kukulka, Michael, et al.
Publicado: (2011)

Bioavailability of dexlansoprazole delayed-release capsule granules when administered via nasogastric tube or orally via syringe
por: Kukulka, Michael, et al.
Publicado: (2018)

Pharmacokinetics and safety of dexlansoprazole MR in pediatric patients with symptomatic gastroesophageal reflux disease
por: Kukulka, Michael, et al.
Publicado: (2014)

First-week clinical responses to dexlansoprazole 60 mg and esomeprazole 40 mg for the treatment of grades A and B gastroesophageal reflux disease
por: Liang, Chih-Ming, et al.
Publicado: (2017)

Bioavailability of everolimus administered as a single 5 mg tablet versus five 1 mg tablets: a randomized, open-label, two-way crossover study of healthy volunteers
por: Thudium, Karen, et al.
Publicado: (2015)

Clinical efficacy of 60-mg dexlansoprazole and 40-mg esomeprazole after 24 weeks for the on-demand treatment of gastroesophageal reflux disease grades A and B: a prospective randomized trial
por: Chiang, Hung-Hsien, et al.
Publicado: (2019)

The Use of Capsule Endoscopy to Determine Tablet Disintegration In Vivo
por: Blaabjerg, Lasse I., et al.
Publicado: (2020)

2229. Relative Bioavailability of a Single Oral Dose of SUBA-Itraconazole 65 mg Capsule Compared with Conventional Itraconazole 100 mg Capsule Administered Under Fasted and Fed Conditions in Healthy Adult Volunteers
por: Mudge, Stuart, et al.
Publicado: (2019)

Relative Bioavailability and Bioequivalence of Brivaracetam 10 mg/mL Oral Solution and 50‐mg Film‐Coated Tablet
por: Otoul, Christian, et al.
Publicado: (2016)

Comparative Efficacy of Super Bioavailable Itraconazole Capsules 50 mg vs 65 mg Twice Daily in the Management of Glabrous Tinea
por: Shah, Bela, et al.
Publicado: (2023)

Bioavailability Evaluation of Venetoclax Lower-Strength Tablets and Oral Powder Formulations to Establish Interchangeability with the 100 mg Tablet
por: Badawi, Mohamed, et al.
Publicado: (2022)

Interchangeability of Two 500 Mg Amoxicillin Capsules with One 1000 Mg Amoxicillin Tablet After a Single Oral Administration
por: Zaid, A. N., et al.
Publicado: (2010)

Safety and pharmacokinetic comparison between fenofibric acid 135 mg capsule and 110 mg enteric-coated tablet in healthy volunteers
por: Seo, Yu-Bin, et al.
Publicado: (2023)

Delayed release dexlansoprazole in the treatment of GERD and erosive esophagitis
por: Wittbrodt, Eric T, et al.
Publicado: (2009)

An Open-Label Crossover Study of the Pharmacokinetics of the 60-mg Edoxaban Tablet Crushed and Administered Either by a Nasogastric Tube or in Apple Puree in Healthy Adults
por: Duchin, Kenneth, et al.
Publicado: (2017)

Pharmacokinetic/Pharmacodynamic Evaluation of Dexlansoprazole Infusion Injection Compared with Lansoprazole in Healthy Chinese Adults
por: Wu, Lihua, et al.
Publicado: (2019)

A Randomized, Double-Blind Noninferiority Study to Evaluate the Efficacy of the Cabozantinib Tablet at 60 mg Per Day Compared with the Cabozantinib Capsule at 140 mg Per Day in Patients with Progressive, Metastatic Medullary Thyroid Cancer
por: Capdevila, Jaume, et al.
Publicado: (2022)

Formulation Design of Fast Disintegrating Tablets Using Disintegrant Blends
por: Shirsand, S. B., et al.
Publicado: (2010)

Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects
por: Kim, Hyun Chul, et al.
Publicado: (2023)

Bioequivalence study of a new sildenafil 100 mg orodispersible film compared to the conventional film-coated 100 mg tablet administered to healthy male volunteers
por: Radicioni, Milko, et al.
Publicado: (2017)

A relative bioavailability study of 500 mg calcium p-aminosalicylate film coating tablet in healthy individuals
por: Cheng, Chinhwa, et al.
Publicado: (2013)

Comparative pharmacokinetics between two tablets of tramadol 37.5 mg/acetaminophen 325 mg and one tablet of tramadol 75 mg/acetaminophen 650 mg for extended-release fixed-dose combination
por: Kim, Hyun Chul, et al.
Publicado: (2022)

Analgesic effect of oral paracetamol 1000 mg/ibuprofen 400 mg, paracetamol 1000 mg/codeine 60 mg, paracetamol 1000 mg/ibuprofen 400 mg/codeine 60 mg, or placebo on acute postoperative pain: a single-dose, randomized, and double-blind study
por: Lyngstad, Gaute, et al.
Publicado: (2023)

The Bioequivalence of Tafamidis 61‐mg Free Acid Capsules and Tafamidis Meglumine 4 × 20‐mg Capsules in Healthy Volunteers
por: Lockwood, Peter A., et al.
Publicado: (2020)

Comparison of Pharmacodynamics between Tegoprazan and Dexlansoprazole Regarding Nocturnal Acid Breakthrough: A Randomized Crossover Study
por: Han, Sungpil, et al.
Publicado: (2023)

The Pharmacokinetics and Relative Bioavailability of Mepolizumab 100 mg Liquid Formulation Administered Subcutaneously to Healthy Participants: A Randomized Trial
por: Shabbir, Shaila, et al.
Publicado: (2019)

Enhancing the Low Oral Bioavailability of Sulpiride via Fast Orally Disintegrating Tablets: Formulation, Optimization and In Vivo Characterization
por: M. Tawfeek, Hesham, et al.
Publicado: (2020)

A comparison of preference for and efficacy of tablet formulations of sumatriptan (50 mg and 100 mg), naratriptan (2.5 mg), rizatriptan (10 mg), and zolmitriptan (2.5 mg) in the acute treatment of migraine
por: Dahlöf, Carl, et al.
Publicado: (2004)

Exploring the Island of Inversion with the d ($^{30}$Mg, p) $^{31}$Mg reaction
por: Bildstein, Vinzenz
Publicado: (2013)

Amikacin/dexlansoprazole: Laryngitis: case report
Publicado: (2021)

Effect of a Disintegration Mechanism on Wetting, Water Absorption, and Disintegration Time of Orodispersible Tablets
por: Pabari, RM, et al.
Publicado: (2012)

A Phase 1, randomized, open-label crossover study to evaluate the safety and pharmacokinetics of 400 mg albaconazole administered to healthy participants as a tablet formulation versus a capsule formulation
por: van Rossem, Koen, et al.
Publicado: (2013)

"Safe" Coulomb Excitation of $^{30}$Mg
por: Niedermaier, O., et al.
Publicado: (2004)

Efficacy and safety of a novel delayed-release risedronate 35 mg once-a-week tablet
por: McClung, M. R., et al.
Publicado: (2011)

Proton resonance elastic scattering of $^{30}$Mg for single particle structure of $^{31}$Mg
por: Imai, N, et al.
Publicado: (2011)

Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets
por: Remya, KS, et al.
Publicado: (2010)

The practical approach to the evaluation of methods used to determine the disintegration time of orally disintegrating tablets (ODTs)
por: Brniak, Witold, et al.
Publicado: (2015)

Rapid disintegrating tablets of simvastatin dispersions in polyoxyethylene–polypropylene block copolymer for maximized disintegration and dissolution
por: Balata, Gehan F, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0fishborer80ekj1ijlmaomjvp