Cargando…

Reduction of neutrophilic lung inflammation by inhalation of the compatible solute ectoine: a randomized trial with elderly individuals

BACKGROUND: Compatible solutes are natural substances that are known to stabilize cellular functions. Preliminary ex vivo and in vivo studies demonstrated that the compatible solute ectoine restores natural apoptosis rates of lung neutrophils and contributes to the resolution of lung inflammation. D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Unfried, Klaus, Krämer, Ursula, Sydlik, Ulrich, Autengruber, Andrea, Bilstein, Andreas, Stolz, Sabine, Marini, Alessandra, Schikowski, Tamara, Keymel, Stefanie, Krutmann, Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076798/ https://www.ncbi.nlm.nih.gov/pubmed/27799756 http://dx.doi.org/10.2147/COPD.S115061

Ejemplares similares

The Compatible Solute Ectoine Reduces the Exacerbating Effect of Environmental Model Particles on the Immune Response of the Airways
por: Unfried, Klaus, et al.
Publicado: (2014)

Signalling-Dependent Adverse Health Effects of Carbon Nanoparticles Are Prevented by the Compatible Solute Mannosylglycerate (Firoin) In Vitro and In Vivo
por: Autengruber, Andrea, et al.
Publicado: (2014)

Ectoine-Containing Inhalation Solution versus Saline Inhalation Solution in the Treatment of Acute Bronchitis and Acute Respiratory Infections: A Prospective, Controlled, Observational Study
por: Tran, Binh-Hai, et al.
Publicado: (2019)

Effectiveness of Ectoin lozenges on oropharyngeal allergic symptoms
por: Khachouk, Rawan, et al.
Publicado: (2022)

Ectoine from Bacterial and Algal Origin Is a Compatible Solute in Microalgae
por: Fenizia, Simona, et al.
Publicado: (2020)

Preventing carbon nanoparticle-induced lung inflammation reduces antigen-specific sensitization and subsequent allergic reactions in a mouse model
por: Kroker, Matthias, et al.
Publicado: (2015)

Ectoine in the Treatment of Irritations and Inflammations of the Eye Surface
por: Bilstein, Andreas, et al.
Publicado: (2021)

The Effectiveness of the Bacteria Derived Extremolyte Ectoine for the Treatment of Allergic Rhinitis
por: Bilstein, Andreas, et al.
Publicado: (2021)

Meta-Analysis of the Efficacy of Ectoine Nasal Spray in Patients with Allergic Rhinoconjunctivitis
por: Eichel, Andrea, et al.
Publicado: (2014)

Protective effects of compatible solute ectoine against ethanol-induced toxic alterations in Daphnia magna
por: Bownik, Adam, et al.
Publicado: (2018)

Improved salt tolerance of Synechococcus elongatus PCC 7942 by heterologous synthesis of compatible solute ectoine
por: Dong, Zhengxin, et al.
Publicado: (2023)

Effects of ectoine containing nasal spray and eye drops on symptoms of seasonal allergic rhinoconjunctivitis
por: Salapatek, Anne M., et al.
Publicado: (2021)

The inflammation-reducing compatible solute ectoine does not impair the cytotoxic effect of ionizing radiation on head and neck cancer cells
por: Rieckmann, Thorsten, et al.
Publicado: (2019)

Ectoine lozenges in the treatment of acute viral pharyngitis: a prospective, active-controlled clinical study
por: Dao, Van-Anh, et al.
Publicado: (2019)

Observational study investigating Ectoin(®) Rhinitis Nasal Spray as natural treatment option of acute rhinosinusitis compared to treatment with Xylometazoline
por: Werkhäuser, Nina, et al.
Publicado: (2021)

Noninterventional Open-Label Trial Investigating the Efficacy and Safety of Ectoine Containing Nasal Spray in Comparison with Beclomethasone Nasal Spray in Patients with Allergic Rhinitis
por: Sonnemann, Uwe, et al.
Publicado: (2014)

Treatment of Allergic Rhinitis with Ectoine Containing Nasal Spray and Eye Drops in Comparison with Azelastine Containing Nasal Spray and Eye Drops or with Cromoglycic Acid Containing Nasal Spray
por: Werkhäuser, Nina, et al.
Publicado: (2014)

Raman Spectroscopic Signature of Ectoine Conformations in Bulk Solution and Crystalline State
por: Solomun, Tihomir, et al.
Publicado: (2020)

Radiochemotheraphy-induced oral mucositis: Ectoin solution as a new treatment
por: Fondevilla, Adriana, et al.
Publicado: (2022)

Applicability of the Global Lung Initiative 2012 Reference Values for Spirometry for Longitudinal Data of Elderly Women
por: Hüls, Anke, et al.
Publicado: (2016)

Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation
por: Peuschel, Henrike, et al.
Publicado: (2012)

Involvement of EupR, a response regulator of the NarL/FixJ family, in the control of the uptake of the compatible solutes ectoines by the halophilic bacterium Chromohalobacter salexigens
por: Rodríguez-Moya, Javier, et al.
Publicado: (2010)

Prevention of Polymorphic Light Eruption Afforded by a Very High Broad-Spectrum Protection Sunscreen Containing Ectoin
por: Duteil, Luc, et al.
Publicado: (2022)

The Influence of Large-Scale Airborne Particle Decline and Traffic-Related Exposure on Children’s Lung Function
por: Sugiri, Dorothea, et al.
Publicado: (2006)

Efficacy and tolerability of an ectoine mouth and throat spray compared with those of saline lozenges in the treatment of acute pharyngitis and/or laryngitis: a prospective, controlled, observational clinical trial
por: Müller, Dörte, et al.
Publicado: (2016)

Estimating the Relative Contribution of Environmental and Genetic Risk Factors to Different Aging Traits by Combining Correlated Variables into Weighted Risk Scores
por: Wigmann, Claudia, et al.
Publicado: (2022)

Ectoine degradation pathway in halotolerant methylotrophs
por: Reshetnikov, Aleksander S., et al.
Publicado: (2020)

Effectiveness, Tolerability, and Safety of Ectoine-Containing Mouthwash Versus Those of a Calcium Phosphate Mouthwash for the Treatment of Chemotherapy-Induced Oral Mucositis: A Prospective, Active-Controlled, Non-interventional Study
por: Dao, Van Anh, et al.
Publicado: (2018)

Illuminating the catalytic core of ectoine synthase through structural and biochemical analysis
por: Czech, Laura, et al.
Publicado: (2019)

Contribution of smoking and air pollution exposure in urban areas to social differences in respiratory health
por: Schikowski, Tamara, et al.
Publicado: (2008)

Protective effects of ectoine on heat-stressed Daphnia magna
por: Adam, Bownik, et al.
Publicado: (2014)

Ectoine protects DNA from damage by ionizing radiation
por: Schröter, M.- A., et al.
Publicado: (2017)

Ectoine can enhance structural changes in DNA in vitro
por: Meyer, S., et al.
Publicado: (2017)

Microbial production of ectoine and hydroxyectoine as high-value chemicals
por: Liu, Mengshuang, et al.
Publicado: (2021)

The promotion and suppression of DNA charge neutralization by the cosolute ectoine
por: Chen, Benteng, et al.
Publicado: (2019)

Detection of gene-environment interactions in the presence of linkage disequilibrium and noise by using genetic risk scores with internal weights from elastic net regression
por: Hüls, Anke, et al.
Publicado: (2017)

Erratum to: Detection of gene-environment interactions in the presence of linkage disequilibrium and noise by using genetic risk scores with internal weights from elastic net regression
por: Hüls, Anke, et al.
Publicado: (2017)

The role of compatible solutes in desiccation resistance of Acinetobacter baumannii
por: Zeidler, Sabine, et al.
Publicado: (2018)

Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily
por: Widderich, Nils, et al.
Publicado: (2016)

Treatment of Rhinitis Sicca Anterior with Ectoine Containing Nasal Spray
por: Sonnemann, Uwe, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_i5vljrtecq1esscd13ve7sa8fe