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Decoration of pH-sensitive copolymer micelles with tumor-specific peptide for enhanced cellular uptake of doxorubicin

To improve the targeting efficacy of hyaluronic acid (HA)-based micelles, pH-sensitive mixed micelles based on HA-g-poly(L-histidine) (PHis) and d-α-tocopheryl polyethylene glycol 2000 copolymers were prepared and decorated with human epidermal growth factor receptor 2 (Her2) peptide, a tumor cell-s...

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Detalles Bibliográficos
Autores principales:	Chen, Qing, Long, Miaomiao, Qiu, Lipeng, Zhu, Mengqin, Li, Zhen, Qiao, Mingxi, Hu, Haiyang, Zhao, Xiuli, Chen, Dawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077130/ https://www.ncbi.nlm.nih.gov/pubmed/27799766 http://dx.doi.org/10.2147/IJN.S111950

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