The Tax-Inducible Actin-Bundling Protein Fascin Is Crucial for Release and Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1 (HTLV-1)

The delta-retrovirus Human T-cell leukemia virus type 1 (HTLV-1) preferentially infects CD4(+) T-cells via cell-to-cell transmission. Viruses are transmitted by polarized budding and by transfer of viral biofilms at the virological synapse (VS). Formation of the VS requires the viral Tax protein and...

Descripción completa

Detalles Bibliográficos
Autores principales: Gross, Christine, Wiesmann, Veit, Millen, Sebastian, Kalmer, Martina, Wittenberg, Thomas, Gettemans, Jan, Thoma-Kress, Andrea K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077169/
https://www.ncbi.nlm.nih.gov/pubmed/27776189
http://dx.doi.org/10.1371/journal.ppat.1005916

Ejemplares similares