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Mucoepidermoid Carcinoma of Palatal Minor Salivary Glands with Intracranial Extension: A Case Report and Literature Review

Mucoepidermoid carcinoma (MEC) is one of the most common malignant tumors of both major and minor salivary glands. Although there are reports of parotid MEC tumors extending intracranially via the facial nerve, intracranial extension from MEC originating from minor salivary glands in the palate has...

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Autores principales: Dossani, Rimal Hanif, Akbarian-Tefaghi, Hesam, Lemonnier, Lori, Mehta, Vikas, Jacobsohn, Jamie A., Guthikonda, Bharat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077716/
https://www.ncbi.nlm.nih.gov/pubmed/27781194
http://dx.doi.org/10.1055/s-0036-1593396
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author Dossani, Rimal Hanif
Akbarian-Tefaghi, Hesam
Lemonnier, Lori
Mehta, Vikas
Jacobsohn, Jamie A.
Guthikonda, Bharat
author_facet Dossani, Rimal Hanif
Akbarian-Tefaghi, Hesam
Lemonnier, Lori
Mehta, Vikas
Jacobsohn, Jamie A.
Guthikonda, Bharat
author_sort Dossani, Rimal Hanif
collection PubMed
description Mucoepidermoid carcinoma (MEC) is one of the most common malignant tumors of both major and minor salivary glands. Although there are reports of parotid MEC tumors extending intracranially via the facial nerve, intracranial extension from MEC originating from minor salivary glands in the palate has not previously been reported. This report presents a case of MEC arising from the minor salivary glands of the palate and extending into the middle fossa via the foramen rotundum with perineural invasion of the maxillary division of the trigeminal nerve. The patient received surgical intervention via a combined otolaryngology and neurosurgery approach to achieve gross total resection of the tumor. This was followed by adjuvant radiotherapy. The epidemiology, histopathology, and treatment of MEC originating from salivary glands are discussed.
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spelling pubmed-50777162016-10-25 Mucoepidermoid Carcinoma of Palatal Minor Salivary Glands with Intracranial Extension: A Case Report and Literature Review Dossani, Rimal Hanif Akbarian-Tefaghi, Hesam Lemonnier, Lori Mehta, Vikas Jacobsohn, Jamie A. Guthikonda, Bharat J Neurol Surg Rep Mucoepidermoid carcinoma (MEC) is one of the most common malignant tumors of both major and minor salivary glands. Although there are reports of parotid MEC tumors extending intracranially via the facial nerve, intracranial extension from MEC originating from minor salivary glands in the palate has not previously been reported. This report presents a case of MEC arising from the minor salivary glands of the palate and extending into the middle fossa via the foramen rotundum with perineural invasion of the maxillary division of the trigeminal nerve. The patient received surgical intervention via a combined otolaryngology and neurosurgery approach to achieve gross total resection of the tumor. This was followed by adjuvant radiotherapy. The epidemiology, histopathology, and treatment of MEC originating from salivary glands are discussed. Georg Thieme Verlag KG 2016-10 /pmc/articles/PMC5077716/ /pubmed/27781194 http://dx.doi.org/10.1055/s-0036-1593396 Text en © Thieme Medical Publishers
spellingShingle Dossani, Rimal Hanif
Akbarian-Tefaghi, Hesam
Lemonnier, Lori
Mehta, Vikas
Jacobsohn, Jamie A.
Guthikonda, Bharat
Mucoepidermoid Carcinoma of Palatal Minor Salivary Glands with Intracranial Extension: A Case Report and Literature Review
title Mucoepidermoid Carcinoma of Palatal Minor Salivary Glands with Intracranial Extension: A Case Report and Literature Review
title_full Mucoepidermoid Carcinoma of Palatal Minor Salivary Glands with Intracranial Extension: A Case Report and Literature Review
title_fullStr Mucoepidermoid Carcinoma of Palatal Minor Salivary Glands with Intracranial Extension: A Case Report and Literature Review
title_full_unstemmed Mucoepidermoid Carcinoma of Palatal Minor Salivary Glands with Intracranial Extension: A Case Report and Literature Review
title_short Mucoepidermoid Carcinoma of Palatal Minor Salivary Glands with Intracranial Extension: A Case Report and Literature Review
title_sort mucoepidermoid carcinoma of palatal minor salivary glands with intracranial extension: a case report and literature review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077716/
https://www.ncbi.nlm.nih.gov/pubmed/27781194
http://dx.doi.org/10.1055/s-0036-1593396
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