Cargando…

The impact of the MYB-NFIB fusion proto-oncogene in vivo

Recurrent fusion of the v-myb avian myelobastosis viral oncogene homolog (MYB) and nuclear factor I/B (NFIB) generates the MYB-NFIB transcription factor, which has been detected in a high percentage of individuals with adenoid cystic carcinoma (ACC). To understand the functional role of this fusion...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mikse, Oliver R., Tchaicha, Jeremy H., Akbay, Esra A., Chen, Liang, Bronson, Roderick T., Hammerman, Peter S., Wong, Kwok-Kin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077968/ https://www.ncbi.nlm.nih.gov/pubmed/27213588 http://dx.doi.org/10.18632/oncotarget.9426

Ejemplares similares

Development and Characterization of MYB-NFIB Fusion Expression in Adenoid Cystic Carcinoma
por: Humtsoe, Joseph O., et al.
Publicado: (2022)

NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer
por: Wu, Nan, et al.
Publicado: (2016)

MYB-NFIB gene fusions identified in archival adenoid cystic carcinoma tissue employing NanoString analysis: an exploratory study
por: McIntyre, John B., et al.
Publicado: (2019)

Association between B-Myb proto-oncogene and the development of malignant tumors
por: Jin, Yuelei, et al.
Publicado: (2021)

Disorders of the cMyb proto-oncogene expression and its significance in the course of ATL development
por: Nakano, Kazumi, et al.
Publicado: (2014)

Analyses of domains and domain fusions in human proto-oncogenes
por: Liu, Qi, et al.
Publicado: (2009)

A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets
por: Gao, Ruli, et al.
Publicado: (2014)

In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential
por: Raffeiner, Philipp, et al.
Publicado: (2014)

Acquisition of an oncogenic fusion protein serves as an initial driving mutation by inducing aneuploidy and overriding proliferative defects
por: Loupe, Jacob M., et al.
Publicado: (2016)

Ligand associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3 dependent cancer cells
por: Wang, Jun, et al.
Publicado: (2014)

MYB Proto-oncogene-like 1-TWIST1 Axis Promotes Growth and Metastasis of Hepatocellular Carcinoma Cells
por: Xie, Binhui, et al.
Publicado: (2020)

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis
por: Lunardi, Andrea, et al.
Publicado: (2014)

c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors
por: Flanagan, Kevin C., et al.
Publicado: (2017)

Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways
por: Jain, Payal, et al.
Publicado: (2017)

MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells
por: Kharbanda, Akriti, et al.
Publicado: (2014)

Transcription factor and microRNA interactions in lung cells: an inhibitory link between NK2 homeobox 1, miR-200c and the developmental and oncogenic factors Nfib and Myb
por: Tagne, Jean-Bosco, et al.
Publicado: (2015)

Role of proto-oncogene activation in carcinogenesis.
por: Anderson, M W, et al.
Publicado: (1992)

The Biology of the Ets1 Proto-Oncogene
por: Dittmer, Jürgen
Publicado: (2003)

The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma
por: Durall, R. Taylor, et al.
Publicado: (2023)

Troponin-I enhances and is required for oncogenic overgrowth
por: Casas-Tintó, Sergio, et al.
Publicado: (2016)

Oncogenes, Proto-Oncogenes, and Lineage Restriction of Cancer Stem Cells
por: Brown, Geoffrey
Publicado: (2021)

Comparison of SARS-CoV-2 RT-PCR on a high-throughput molecular diagnostic platform and the cobas SARS-CoV-2 test for the diagnostic of COVID-19 on various clinical samples
por: Opota, Onya, et al.
Publicado: (2020)

MEDB-89. Elucidation of the Oncogenic role of Nuclear Factor I/B (NFIB) in group 3 medulloblastoma
por: Perumal, Naveenkumar, et al.
Publicado: (2022)

Expression of ret Proto‐oncogene in Human Neuroblastomas
por: Nagao, Minako, et al.
Publicado: (1990)

Roles of the RET Proto-oncogene in Cancer and Development
por: Takahashi, Masahide, et al.
Publicado: (2020)

PBF, a Proto-oncogene in Esophageal Carcinoma
por: Lian, Shi-hai, et al.
Publicado: (2019)

Palbociclib resistance confers dependence on an FGFR-MAP kinase-mTOR-driven pathway in KRAS-mutant non-small cell lung cancer
por: Haines, Eric, et al.
Publicado: (2018)

Integrated in vivo genetic and pharmacologic screening identifies co-inhibition of EGRF and ROCK as a potential treatment regimen for triple-negative breast cancer
por: Iskit, Sedef, et al.
Publicado: (2016)

Activation of Cell Cycle Arrest and Apoptosis by the Proto-Oncogene Pim-2
por: Levy, Daphna, et al.
Publicado: (2012)

HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice
por: Esser, Alison K., et al.
Publicado: (2017)

MYB proto-oncogene like 2 promotes hepatocellular carcinoma growth and glycolysis via binding to the Optic atrophy 3 promoter and activating its expression
por: Liu, Miao, et al.
Publicado: (2022)

Activation of proto-oncogenes in human and mouse lung tumors.
por: Reynolds, S H, et al.
Publicado: (1991)

The Proto-Oncogene TWIST1 Is Regulated by MicroRNAs
por: Nairismägi, Maarja-Liisa, et al.
Publicado: (2013)

Distribution of RET proto‐oncogene variants in children with appendicitis
por: Schultz, Jurek, et al.
Publicado: (2022)

Laser nanostructured gold biosensor for proto-oncogene detection
por: Hughes, Cian, et al.
Publicado: (2023)

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways
por: Saiki, Anne Y., et al.
Publicado: (2014)

Oncogenic KRAS activates an embryonic stem cell-like program in human colon cancer initiation
por: Le Rolle, Anne-France, et al.
Publicado: (2016)

BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia
por: Li, Yulin, et al.
Publicado: (2016)

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer
por: Oran, Amanda R., et al.
Publicado: (2016)

A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling
por: Matissek, Stephan J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_induc87cfqp5or3tesp4nu357n