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Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice

The purpose of this study was to evaluate the effect of dichloroacetate (DCA) treatment for brain injury in neonatal mice after hypoxia ischemia (HI) and the possible molecular mechanisms behind this effect. Postnatal day 9 male mouse pups were subjected to unilateral HI, DCA was injected intraperit...

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Detalles Bibliográficos
Autores principales: Sun, Yanyan, Li, Tao, Xie, Cuicui, Zhang, Yaodong, Zhou, Kai, Wang, Xiaoyang, Blomgren, Klas, Zhu, Changlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077971/
https://www.ncbi.nlm.nih.gov/pubmed/27153546
http://dx.doi.org/10.18632/oncotarget.9150