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Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice
The purpose of this study was to evaluate the effect of dichloroacetate (DCA) treatment for brain injury in neonatal mice after hypoxia ischemia (HI) and the possible molecular mechanisms behind this effect. Postnatal day 9 male mouse pups were subjected to unilateral HI, DCA was injected intraperit...
Autores principales: | Sun, Yanyan, Li, Tao, Xie, Cuicui, Zhang, Yaodong, Zhou, Kai, Wang, Xiaoyang, Blomgren, Klas, Zhu, Changlian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077971/ https://www.ncbi.nlm.nih.gov/pubmed/27153546 http://dx.doi.org/10.18632/oncotarget.9150 |
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