IL-10 control of CD11c(+) myeloid cells is essential to maintain immune homeostasis in the small and large intestine

Although IL-10 promotes a regulatory phenotype of CD11c(+) dendritic cells and macrophages in vitro, the role of IL-10 signaling in CD11c(+) cells to maintain intestinal tolerance in vivo remains elusive. To this aim, we generated mice with a CD11c-specific deletion of the IL-10 receptor alpha (Cd11...

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Detalles Bibliográficos
Autores principales: Girard-Madoux, Mathilde J.H., Ober-Blöbaum, Juliane L., Costes, Léa M.M., Kel, Junda M., Lindenbergh, Dicky J., Brouwers-Haspels, Inge, Heikema, Astrid P., Samsom, Janneke N., Clausen, Björn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077993/
https://www.ncbi.nlm.nih.gov/pubmed/27027442
http://dx.doi.org/10.18632/oncotarget.8337

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